Efavirenz is indicated in antiviral combination treatment of human immunodeficiency virus 1
(HIV 1) infected adults, adolescents and children 3 months of age and older and weighing at least 3.5 kg.
Efavirenz has not been adequately studied in patients with advanced HIV disease, namely in patients with CD4 counts < 50 cells/mm 3, or after failure of protease inhibitor (PI) containing
regimens. Although cross resistance of Efavirenz with PIs has not been documented, there are at present insufficient data on the efficacy of subsequent use of PI based combination therapy after
failure of regimens containing Efavirenz.
For a summary of clinical and pharmacodynamic information.
Treatment of essential hypertension.
AMOTAN-H FC TABLET
Add-on therapy
OLMEXA PLUS is indicated in adult patients whose blood pressure is not adequately controlled on the combination of
olmesartan medoxomil and amlodipine taken as dual-component formulation.
Substitution therapy
OLMEXA PLUS is indicated as substitution therapy in adult patients whose blood pressure is adequately controlled on the
combination of olmesartan medoxomil, amlodipine and hydrochlorothiazide, taken as a dual-component (Olmesartan medoxomil and amlodipine or olmesart
Treatment of essential hypertension.
AMOTAN-H FC TABLET
Add-on therapy
OLMEXA PLUS is indicated in adult patients whose blood pressure is not adequately controlled on the combination of
olmesartan medoxomil and amlodipine taken as dual-component formulation.
Substitution therapy
OLMEXA PLUS is indicated as substitution therapy in adult patients whose blood pressure is adequately controlled on the
combination of olmesartan medoxomil, amlodipine and hydrochlorothiazide, taken as a dual-component (Olmesartan medoxomil and amlodipine or olmesart
Treatment of essential hypertension.
AMOTAN-H FC TABLET
Add-on therapy
OLMEXA PLUS is indicated in adult patients whose blood pressure is not adequately controlled on the combination of
olmesartan medoxomil and amlodipine taken as dual-component formulation.
Substitution therapy
OLMEXA PLUS is indicated as substitution therapy in adult patients whose blood pressure is adequately controlled on the
combination of olmesartan medoxomil, amlodipine and hydrochlorothiazide, taken as a dual-component (Olmesartan medoxomil and amlodipine or olmesart
Treatment of essential hypertension.
AMOTAN-H FC TABLET
Add-on therapy
OLMEXA PLUS is indicated in adult patients whose blood pressure is not adequately controlled on the combination of
olmesartan medoxomil and amlodipine taken as dual-component formulation.
Substitution therapy
OLMEXA PLUS is indicated as substitution therapy in adult patients whose blood pressure is adequately controlled on the
combination of olmesartan medoxomil, amlodipine and hydrochlorothiazide, taken as a dual-component (Olmesartan medoxomil and amlodipine or olmesart
Elacestrant Dihydrochloride monotherapy is indicated for the treatment of postmenopausal women, and men, with estrogen receptor (ER)-positive, HER2-negative, locally advanced or metastatic breast cancer with an activating ESR1 mutation who have disease progression following at least line of endocrine therapy including a CDK 4/6 inhibitor for at least 12 months.
This indication is approved based on progression free survival. Continued approval of this indication may be contingent upon verification and description of clinical benefit (overall survival) in the confirmatory trials.
Bupivacaine Hydrochloride Anhydrous 0.5% is indicated in adults and children of all ages for intrathecal (subarachnoid) spinal anaesthesia for surgery (urological and lower limb surgery lasting 2–3 hours, abdominal
surgery lasting 45–60 minutes).
Bupivacaine Hydrochloride Anhydrous is a long-acting anaesthetic agent of the amide type. Bupivacaine has a rapid onset of action and long duration. The duration of analgesia in the T10–T12 segments is 2–3 hours.
Bupivacaine Hydrochloride Anhydrous produces a moderate muscular relaxation of the lower extremities lasting 2–2.5 hours. The motor blockade of the abdominal muscles makes the solution suitable for performance
of abdominal surgery lasting 45–60 minutes. The duration of the motor blockade does not exceed the duration of analgesia. The cardiovascular effects of bupivacaine are similar or less than those seen with other spinal agents. Bupivacaine is exceptionally well tolerated by all tissues with which it comes in contact.
Malignant pleural mesothelioma
Pemetrexed Disodium in combination with cisplatin is indicated for the treatment of chemotherapy naïve patients with unresectable malignant pleural mesothelioma.
Non-small cell lung cancer
Pemetrexed Disodium in combination with cisplatin is indicated for the first line treatment of patients with locally advanced or metastatic non-small cell lung cancer other than predominantly squamous cell histology.
Pemetrexed Disodium is indicated as monotherapy for the maintenance treatment of locally advanced or metastatic non-small cell lung cancer other than predominantly squamous cell histology in patients whose disease has not progressed immediately following platinum-based chemotherapy.
Pemetrexed Disodium is indicated as monotherapy for the second line treatment of patients with locally advanced or metastatic non-small cell lung cancer other than predominantly squamous cell histology.
Registration
Generic Drug
MenQuadfi
Meningococcal (Serogroup A) Polysaccharide 10 ug, Meningococcal (Serogroup C) Polysaccharide 10 ug, Meningococcal (Serogroup Y) Polysaccharide 10 ug, Meningococcal (Serogroup W135) Polysaccharide 10 ug
Meningococcal (Serogroup A) Polysaccharide 10 ug, Meningococcal (Serogroup C) Polysaccharide 10 ug, Meningococcal (Serogroup Y) Polysaccharide 10 ug, Meningococcal (Serogroup W135) Polysaccharide 10 ug
الاستخدامات الطبية المعتمدة
MenQuadfi is indicated for active immunization of individuals from the age of 12 months and older against invasive meningococcal disease caused by Neisseria meningitidis serogroups A, C, W, and Y.
