Drug Clinical Trials List

Study Title	Study Sponsor	Status	Study Drug	Trial Phase	Study Protocol Number	Site
A phase III randomized open-label multi-center study of ruxolitinib vs. best available therapy in patients with corticosteroid-refractory acute graft vs. host disease after allogenic stem cell transplantation	Novartis	Completed	Ruxolitinib (INC424) (Jakavi)	3	CINC424C2301	KFSH&RC-R
A phase III randomized open-label multi-center study of ruxolitinib vs. best available therapy in patients with corticosteroid-refractory chronic graft versus host disease after allogenic stem cell transplantation	Novartis	Ongoing	Ruxolitinib (INC424) (Jakavi)	3	CINC424D2301	KFSH & RC-R
A Phase III Multicenter, Double-Blind, Randomized, Placebo- Controlled Clinical Trial to Evaluate the Safety and Efficacy of MK-0431A XR (a Fixed-Dose Combination Tablet of Sitagliptin and Extended-Release Metformin) in Pediatric Subjects with Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Monotherapy	MSD	Completed	SITAGLIPTIN/ METFORMIN XR	3	MK0431A XR-289	KKUH
"A Phase III Double-blind Randomised Study Assessing the Efficacy and Safety of Capivasertib + Paclitaxel Versus Placebo + Paclitaxel as First-line Treatment for Patients with Histologically Confirmed, Locally Advanced (Inoperable) or Metastatic Triple-Negative Breast Cancer (TNBC)"	AstraZeneca	Ongoing	Capivasertib	3	D3614C00001	KFSH-D
A phase II, multicenter, open label study of treatment escalation to ACVD (Adriamycin, Cyclophosphamide, Vinblastine and Dacarbazine) and Brentuximab-Vedotin in advanced-stage Hodgkin Lymphoma patients with a positive interim PET scan after 2 ABVD cycles (OPTIMIST study)	KAIMRC	Ongoing	DOXORUBICIN HYDROCHLORIDE	2	RC16/150	NGHA-R
A Phase II Study to examine the efficacy and safety of a new drug called Sevuparin on resolution of painful vaso-occlusive crisis in patients with sickle-cell disease.	Modus Therapeutics AB	Ongoing	Sevuparin	3	TVOC01	KKUH
A phase II randomized study of the combination of Ribociclib plus goserelin acetate with Hormonal Therapy versus physician choice chemotherapy in premenopausal or perimenopausal patients with hormone receptorpositive/HER2-negative inoperable locally advanced or metastatic breast cancer – RIGHT Choice Study.	Novartis	Terminated	ribociclib	2	CLEE011A3201C	King Faisal Specialist Hospital and Research Center (Riyadh)
"A Phase II open-label, single-arm, multi-center study of ruxolitinib added to corticosteroids in pediatric subjects with moderate and severe chronic graft vs. host disease after allogeneic stem cell transplantation"	Novartis	Completed	ruxolitinib	2	CINC424G12201	KFSH&RC-R
A Phase Ib study to determine the safety and immunogenicity of the candidate Middle East Res-piratory Syndrome Coronavirus (MERS-CoV) vaccine ChAdOx1 MERS in healthy adult Middle Eastern volunteers	KAIMRC	Ongoing	vaccine ChAdOx1 MERS	1b	CT18/004/R	NGHA-R
"A Phase 3B, Randomized, Double-Blind Clinical Trial to Evaluate the Efficacy and Safety of Abatacept SC in Combination with Methotrexate Compared to Methotrexate Monotherapy in Achieving Clinical Remission in Adults with Early Rheumatoid Arthritis who are Methotrexate Naive"	Bristol-Myers Squibb	Terminated	Abatacept	3b	IM101550	KFMC