Drug Clinical Trials List

Study Title	Study Sponsor	Status	Study Drug	Trial Phase	Study Protocol Number	Site
Phase 3b, Open-label, Multicenter, Single-dose Study Investigating Efficacy and Safety of CSL222 (Etranacogene Dezaparvovec) Gene Therapy Administered to Adult Subjects with Severe or Moderately Severe Hemophilia B with Detectable Pretreatment AAV5 Neutralizing Antibodies	CSL Behring LLC	Ongoing	HEMGENIX (etranacogene dezaparvovec)	3b	CSL222_3005	King Faisal Specialist Hospital and Research Center (Riyadh)
REAL-WORLD, LONG-TERM DATA COLLECTION TO GAIN CLINICAL INSIGHTS INTO ROCHE OPHTHALMOLOGY PRODUCTS (VOYAGER STUDY)- COMPLETE	Roche	Ongoing	Vabysmo	4	MR41927	King Abdulaziz Medical City NG (Jeddah)
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Ravulizumab in Adult Participants with Immunoglobulin A Nephropathy (IgAN)	AstraZeneca	Ongoing	Ravulizumab	3	D928FC00001	King Faisal Specialist Hospital and Research Center (Riyadh),King Fahad Specialist Hospital (Dammam)
A Multicenter, Open-label, Single-arm, Phase 3 Long-Term Extension Study to Evaluate Continuous Safety and Efficacy of BIIB059 (Litifilimab) in Adult Participants with Active Subacute Cutaneous Lupus Erythematosus and/or Chronic Cutaneous Lupus Erythematosus with or without Systemic Manifestations and Refractory and/or Intolerant to Antimalarial Therapy (AMETHYST LTE)	Biogen Idec Research Limited	Ongoing	Litifilimab	3	230LE305	King Faisal Specialist Hospital and Research Center (Riyadh), King Khalid University Hospital (Riyadh)
SODium BICarbonate for Metabolic Acidosis in the Intensive Care Unit (SODa-BIC): A multicentre, randomised, double-blind clinical trial	King Abdullah International Medical Research Center (KAIMRC)	Ongoing	SODIUM BICARBONATE	3	SCT23R/012/10	King Abdulaziz Medical City NG (Riyadh)
Real-World Evidence Study for the Safety and Effectiveness of Ribociclib in Combination with Hormonal Therapy in Patients with HR+/HER2- Advanced or Metastatic Breast Cancer in the Middle East Region	Novartis	Ongoing	Ribociclib	4	CLEE011AIC	King Faisal Specialist Hospital and Research Center (Riyadh)
The Effect of Empagliflozin (SGLT2 Inhibitor) in Pulmonary Arterial Hypertension: A Single Arm Prospective Interventional Study	King Faisal Specialist Hospital & Research Centre Riyadh, Saudi Arabia	Ongoing	Empagliflozin	2	2231281	King Faisal Specialist Hospital and Research Center (Riyadh)
A Phase 3, Open-label, Uncontrolled Study to Evaluate the Activity, Safety, Pharmacokinetics and Pharmacodynamics of Roxadustat for the Treatment of Anemia in Pediatric Participants with Chronic Kidney Disease	Astellas Pharma Global Development Inc	Ongoing	roxadustat	3	1517-CL-1003	King Faisal Specialist Hospital and Research Center (Riyadh),King Fahad Specialist Hospital (Dammam)
A multicenter real-world evidence study with retrospective chart review and cross-sectional survey to evaluate the satisfaction and benefits of long-term repeated BOTOX treatment for upper facial lines	AbbVie	Ongoing	Botox	4	H24-500	Derma Clinic
Phase II, Prospective, Randomized, placebo-controlled, double-blind study.Evaluation of Phytochemical properties and Phytotherapeutic Potential of Boswellia carteri Birdw. in Psoriasis	PI Initiated	Ongoing	boswellia carteri (Psorelia)	2	E-23-7585	King Khalid University Hospital (Riyadh)