Drug Clinical Trials List

Study Title	Study Sponsor	Status	Study Drug	Trial Phase	Study Protocol Number	Site
Fluid Management in Sickle Cell Disease Vaso-occlusive Crisis: Restrictive versus Liberal Strategies: A Randomized Controlled Trial (FLASC Trial)	PI initiative	Ongoing	Sodium Chloride / Lactated Ringers	4	FLASC01	King Fahad University Hospital (Al-Khobar)
A Phase III, Multicenter, Double-Blind, Placebo-Controlled, Treat-Through Study To Assess The Efficacy And Safety of Induction and Maintenance Therapy with Ro7790121 in Patients with Moderately to Severely Active Crohn's Disease	Roche / IQVIA	Ongoing	Ro7790121	3	GA45331	King Faisal Specialist Hospital and Research Center (Riyadh), King Saud Medical City (Riyadh)
A randomized, double-blinded placebo-controlled, phase 3, parallel-group design study evaluating the efficacy and safety of Efgartigimod PH20 SC Administered by prefilled syringe in adults participants with ocular MG	Argenx BV / Balsam	Ongoing	Efgartigimod	3	ARGX-113-2315	King Faisal Specialist Hospital and Research Center (Riyadh)
Long-Term, Observational, Global Registry of Patients With Generalized Myasthenia Gravis Who Have Received Treatment With Complement C5 Inhibition Therapies	AstraZeneca/ IQVIA	Ongoing	Eculizumab	3	ALXN-MG-50	Aseer Hospital (Abha), King Faisal Specialist Hospital and Research Center (Riyadh), King Abdulaziz Medical City NG (Riyadh)
A Phase 3 Randomized, Double-Blinded, Placebo-Controlled Multicenter Trial with Open Label Extension to Evaluate the Efficacy, Safety, and Tolerability of Efgartigimod PH20 Subcutaneous Administered by Prefilled Syringe in Adult Patients with Primary Sjögren’s Disease	Argenx BV / IQVIA	Ongoing	Efgartigimod	3	ARGX-113-2306	King Faisal Specialist Hospital and Research Center (Riyadh) , King Khalid University Hospital (Riyadh)
A Phase 2, randomized, open-label, controlled study to evaluate the efficacy and safety of rapcabtagene autoleucel versus comparator in participants with severe active Granulomatosis with Polyangiitis (GPA) or Microscopic Polyangiitis (MPA)	Novartis	Ongoing	Rapcabtagene Autoleucel (YTB323)	2	CYTB323I12201	King Faisal Specialist Hospital and Research Center (Riyadh)
An Open-label Extension Study Evaluating the Long-term Safety and Efficacy of Seralutinib Orally Inhaled for the Treatment of Pulmonary Arterial Hypertension (PAH)	GB002, Inc / Balsam	Ongoing	Seralutinib	3	GB002-3102	King Faisal Specialist Hospital and Research Center (Riyadh) , King Fahad Medical City (Riyadh)
A Phase 3 Study to Evaluate the Efficacy, Safety, and Tolerability of VX-880 in Subjects With Type 1 Diabetes With a Kidney Transplant	Vertex / CTI	Ongoing	VX880	3	VX23-880-102	King Faisal Specialist Hospital and Research Center (Riyadh) , King Abdulaziz Medical City NG (Riyadh)
The prolonged effect of spinal dexmedetomidine versus Intravenous dexmedetomidine on spinal anesthesia using isobaric Bupivacaine in Orthopedic Surgeries, Randomized clinical trial	King Abdullah International Medical Research Center (Riyadh)	Ongoing	Dexmedetomidine	3	ICTR24/001/11	King Abdulaziz Medical City NG (Riyadh)
Registry-based study of patients treated with exagamglogene autotemcel (exa-cel) in the Kingdom of Saudi Arabia	Vertex	Ongoing	Exagamglogene autotemcel (Casgevy)	4	290-103	-