Drug Clinical Trials List

Study Title	Study Sponsor	Status	Study Drug	Trial Phase	Study Protocol Number	Site
An international randomised trial of additional treatments for COVID-19 in hospitalised patients who are all receiving the local standard of care	GDRS (MOH)	Ongoing	• Hydroxychloroquine sulphate• CHLOROQUINE PHOSPHATE• Lopinavir/Ritonavir • Remdesivir• Interferon beta-1b	3	version 8	Qatif Central Hospital, Dammam Medical Complex, Ohud hospital (Medina), Al-Noor Specialist Hospital (Makkah), Prince Mohammad bin Abdulaziz hospital (Riyadh)
A phase II, multicenter, open label study of treatment escalation to ACVD (Adriamycin, Cyclophosphamide, Vinblastine and Dacarbazine) and Brentuximab-Vedotin in advanced-stage Hodgkin Lymphoma patients with a positive interim PET scan after 2 ABVD cycles (OPTIMIST study)	KAIMRC	Ongoing	• DOXORUBICIN HYDROCHLORIDE• CYCLOPHOSPHAMIDE• VINBLASTINE SULPHATE • DACARBAZINE• BRENTUXIMAB VEDOTIN	2	RC16/150	King Abdulaziz Medical City NG (Riyadh)
Phase 3, open label, single arm study to evaluate efficacy and safety of FIX gene transfer with PF-06838435 (rAAV-Spark100-hFIX-Padua) in adult male participants with moderately severe to severe hemophilia B (FIX:C<2%) (BeneGene-2)	Pfizer	Ongoing	PF-06838435	3	C0371002	King Faisal Specialist Hospital and Research Center (Riyadh)
An Open-label Extension Study to Evaluate Long-term Efficacy and Safety of A4250 in Children with Progressive Familial Intrahepatic Cholestasis Types 1 and 2 (PEDFIC 2)	Albireo	Ongoing	A4250	3	A4250-008	King Faisal Specialist Hospital and Research Center (Riyadh)
"ALL SCTped 2012 FORUMAllogeneic Stem Cell Transplantation in Children and Adolescents with Acute Lymphoblastic Leukaemia"	KAIMRC	Completed	• BUSULFAN• FLUDARABINE PHOSPHATE• ETOPOSIDE	3	CT17/016/R	King Abdulaziz Medical City NG (Riyadh)
Single arm Phase I/II study of the safety, tolerability and efficacy of the Tocilizumab followed by cisplatin/docetaxel in patients with triple negative locally advanced breast cancer	King Faisal Specialist Hospital and Research Centre	Ongoing	• TOCILIZUMAB (ACTEMRA)• DOCETAXEL (TAXOTERE)• CISPLATIN	2a	2181156	King Faisal Specialist Hospital and Research Center (Riyadh)
Re-challenge therapy with chemotherapy and panitumumab in metastatic colorectal cancer patients treated with an anti-EGFR therapy in 1st line treatment: a phase II multicentre study.	King Abdullah Medical City, Holy Capital	Ongoing	• PANITUMUMAB• OXALIPLATIN• irinotecan• FLOUROURACIL	2	19-504	King Abdullah Medical City (Makkah)
An Open-Label, Randomized, Multicenter, Active-Controlled, Parallel-Group Study to Evaluate the Safety, Tolerability, and Efficacy of BIIB017 in Pediatric Subjects Aged 10 to Less Than 18 Years for the Treatment of Relapsing-Remitting Multiple Sclerosis, With Optional Open-Label Extension	Biogen	Ongoing	Interferon beta-1a	3	105MS306	King Faisal Specialist Hospital and Research Center (Jeddah), King Khalid University Hospital (Riyadh)
"A multicenter, multinational, prospective, interventional,single-arm, Phase IV study evaluating the clinicalefficacy and safety of 26 weeks of treatment with insulin glargine 300 U/mL (Gla-300) in patients with Type 2 diabetes mellitus uncontrolled on basal insulin"	SANOFI	Ongoing	TOUJEO	4	LPS15396	Sultan bin Abdulaziz Humanitarian city (Riyadh)
A prospective Randomized study of General Anesthesia versus Anesthetist Administered sedation for ERCP	King Abdullah Medical City (Makkah)	Ongoing	FENTANYL/ CISATRACURIUM/ SEVOFLURANE	4	18-492	King Abdullah Medical City (Makkah)