Drug Clinical Trials List

Study Title	Study Sponsor	Status	Study Drug	Trial Phase	Study Protocol Number	Site
Prospective, Open-label, Uncontrolled, Phase III Study to Assess the Efficacy and Safety of Octafibrin for On-demand Treatment of Acute Bleeding and to Prevent Bleeding During and After Surgery in Subjects With Congenital Fibrinogen Deficiency	Octapharma	Ongoing	Octafibrin	3	Forma 02	King Khalid University Hospital (Riyadh)
A Multicenter, Open-label, Single-arm Study of a Pertuzumab in Combination With Trastuzumab and a Taxane in First Line Treatment of Patients With HER2- Positive Advanced (Metastatic or Locally Recurrent) Breast Cancer	Roche	Ongoing	Pertuzumab / Trastuzumab / Taxane	3b	MO28047	King Faisal Specialist Hospital and Research Center (Riyadh), King Abdulaziz Medical City NG (Riyadh), King Faisal Specialist Hospital and Research Center (Jeddah)
An Open-Label, Multicenter Study to Evaluate Long-Term Outcomes With ABT-450/Ritonavir/ ABT-267 (ABT-450/r/ABT-267) and ABT-333 With or Without Ribavirin (RBV) in Adults With Genotype 1 Chronic Hepatitis C Virus (HCV) Infection (TOPAZ-I)	AbbVie	Ongoing	ABT-450/r/ABT-267 ABT-333Ribavirin (RBV)	3b	M14-423	King Khalid University Hospital (Riyadh), King Abdulaziz Medical City NG (Jeddah), King Fahad Hospital (Jeddah), King Abdulaziz Medical City NG (Riyadh), King Faisal Specialist Hospital and Research Center (Riyadh)
Risk assesment and mangement of Vte in women at risk of thromboEmbolism during pregnancy and puerperium	Sanofi	Ongoing	N/A	4	OBS14159	King Abdulaziz University Hospital (Jeddah)
The Efficacy and Safety of Ferriprox® for the Treatment of Transfusional Iron Overload in Patients With Sickle Cell Disease or Other Anemias	ApoPharma Inc.	Ongoing	Deferiprone Deferoxamine	3b	LA38-0411	Aseer Central Hospital, King Abdulaziz University Hospital (Jeddah), King Khalid University Hospital (Riyadh)
A Phase III, Multicenter, Double-Blind, Randomized, Placebo-Controlled Clinical Trial to Evaluate the Safety and Efficacy of MK-0431A (A Fixed-Dose Combination Tablet of Sitagliptin and Metformin) in Pediatric Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Therapy (Alone or in Combination With Insulin)	MSD	Ongoing	(Sitagliptin / Metformin)	3	MK0431-170	King Abdulaziz Medical City NG (Riyadh), King Abdulaziz Hospital NG (Al Ahsa)
A PHASE III PROSPECTIVE, TWO-COHORT NON-RANDOMIZED, MULTI-CENTRE, MULTINATIONAL, OPEN LABEL STUDY TO ASSESS THE SAFETY OF ASSISTED- AND SELF-ADMINISTERED SUBCUTANEOUS TRASTUZUMAB AS THERAPY IN PATIENTS WITH OPERABLE HER2-POSITIVE EARLY BREAST CANCER [SafeHer Study]	Roche	Ongoing	trastuzumab	3	MO28048	King Faisal Specialist Hospital and Research Center (Jeddah), King Abdulaziz Medical City NG (Riyadh)
A Phase III Multicenter, Double-Blind, Randomized, Placebo- Controlled Clinical Trial to Evaluate the Safety and Efficacy of MK-0431A XR (a Fixed-Dose Combination Tablet of Sitagliptin and Extended-Release Metformin) in Pediatric Subjects with Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Monotherapy	MSD	Ongoing	SITAGLIPTIN/ METFORMIN XR	3	MK0431A XR-289	King Khalid University Hospital (Riyadh)
A Phase III, Multicenter, Double-Blind, Randomized, Placebo-Controlled Clinical Trial to Evaluate the Safety and Efficacy of Sitagliptin in Pediatric Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control	MSD	Ongoing	Sitagliptin	3	MK0431-083	King Abdulaziz Medical City NG (Riyadh), King Abdulaziz Hospital NG (Al Ahsa), Al-Noor Specialist Hospital (Makkah)
A Multinational, Randomised, Double-Blind, Placebo-Controlled Trial to Evaluate the Effect of Ticagrelor Twice Daily on the Incidence of Cardiovascular Death, Myocardial Infarction or Stroke in Patients With Type 2 Diabetes Mellitus (THEMIS - Effect of Ticagrelor on Health Outcomes in diabEtes Mellitus Patients Intervention Study)	AstraZeneca	Ongoing	Ticagrelor	3b	D513BC00001	King Khalid University Hospital (Riyadh), King Fahad Specialist Hospital (Dammam), King Faisal Specialist Hospital and Research Center (Riyadh), King Faisal Specialist Hospital and Research Center (Jeddah), King Fahad Medical City (Riyadh), King Abdulaziz Medical City NG (Riyadh), King Fahad University Hospital (Al-Khobar), Saud Al-Babtain Cardiac Center (Dammam)