Drug Clinical Trials List

Study Title	Study Sponsor	Status	Study Drug	Trial Phase	Study Protocol Number	Site
Stress Hydrocortisone in Pediatric Septic Shock (The SHIPSS trial)	King Abdullah International Medical Research Center (KAIMRC)	Ongoing	Hydrocortisone	4	SCT22R/009	King Abdulaziz Medical City NG (Riyadh)
iOUTRUN: Patient-Reported OUTcomes of Benralizumab in Real-World Use in Severe EosiNophilic Asthma Patients	AstraZeneca	Ongoing	Benralizumab	4	D3250R0011	King Fahad Medical City (Riyadh) , King Faisal Specialist Hospital and Research Center (Jeddah),International Medical Center (Jeddah)
"Nintedanib in patients with bronchiolitis obliterans syndrome following hematopoietic stem cell transplantation – a multicentre phase II trial"	King Faisal Specialist Hospital & Research Centre Riyadh, Saudi Arabia	Ongoing	NINTEDANIB	2	Amendment 3 F02	King Faisal Specialist Hospital and Research Center (Riyadh)
An open-label, controlled, multi-site, Phase 2 clinical trial to assess the ureagenesis capacity in newborns and infants up to the age of 12 months with neonatal and infantile onset of urea cycle disorders (UCD) using a 15N ammonium chloride tracer compared to newborns and infants without UCD	Unicyte AG,Aawasserstrasse 2, 6370 Oberdorf NW, Switzerland	Rejected	15NH4Cl tracer assay	2	HLSC-UCD-01	King Abdulaziz Medical City NG (Riyadh)
A Phase 2 Open-label, Dose Escalation Study of HST5040 in Subjects with Propionic or Methylmalonic Acidemia Followed by a 6-Month, Randomized, Double-blind, Placebo-controlled, 2-period Crossover Study and an Open-label, Long-term Extension Study	HemoShear Therapeutics,	Terminated	ST5040 (2,2-dimethylbutanoic acid)	4	HST20-CL01	King Faisal Specialist Hospital and Research Center (Riyadh)
An observational disease and clinical outcomes registry of patients with acid lipase (LAL) deficiency	Alexion Pharma	Ongoing	Kanuma	4	ALX-LALD-5	King Faisal Specialist Hospital and Research Center (Riyadh) , King Abdulaziz Medical City NG (Riyadh)
A study comparing the effect and safety of once weekly dosing of somapacitan with daily Norditropin® as well as evaluating long-term safety of somapacitan in a basket study design in children with short stature either born small for gestational age or with Turner syndrome, Noonan syndrome, or idiopathic short stature	Novo Nordisk	Ongoing	Sogroya , Norditropin	3	NN8640-4467	King Faisal Specialist Hospital and Research Center (Riyadh) , King Abdulaziz Medical City NG (Riyadh)
Early Sedation with Dexmedetomidine vs. Placebo in Older Ventilated Critically Ill Patients A Prospective, Multi-Centre, Double-Blind, Randomized, Controlled Trial. SPICE IV	King Abdullah International Medical Research Center (KAIMRC)	Ongoing	DEXMEDETOMIDINE	4	SCT21R/006/04	King Abdulaziz Medical City NG (Riyadh), King Faisal Specialist Hospital and Research Center (Riyadh)
VICTORION REAL: An international prospective Real-world study to evaluate the Effectiveness and Adherence of incLisiran plus standard of care lipid-lowering therapy compared to standard of care therapy alone in patients with primary hypercholesterolemia or mixed dyslipidemia	Novartis	Ongoing	Inclisiran	4	CKJX839A12	Saud Al-Babtain Cardiac Center (Dammam) , King Salman Armed Forces Hospital(Tabuk) , King Fahd Armed Forces Hospital (Jeddah) , Dr. Sulaiman Al-Habib Medical Group Rayan (Riyadh),King Faisal Specialist Hospital and Research Center (Jeddah), Dr. Sulaiman Al-Habib Medical Group Olaya (Riyadh), International Medical Center (Jeddah)
O-SEMA-Fast: A research study to understand how oral semaglutide works in people with type 2 diabetes who plan to fast during Ramadan in the United Arab Emirates, Saudi Arabia, and Kuwait	Novo Nordisk	Ongoing	Semaglutide	4	NN9924-757	Almoosa Specialist Hospital (Alahsa)