Drug Clinical Trials List

Study Title	Study Sponsor	Status	Study Drug	Trial Phase	Study Protocol Number	Site
A Phase 2 study of PHE885, B-cell maturation Antigen (BCMA)-directed CAR-T Cells in adult participants with relapsed and refractory multiple myeloma.	Novartis	Ongoing	PHE885 (CAR-T Cell)	2	CPHE885B12201	King Faisal Specialist Hospital and Research Center (Riyadh)
Stress Hydrocortisone in Pediatric Septic Shock (The SHIPSS trial)	King Abdullah International Medical Research Center (KAIMRC)	Ongoing	Hydrocortisone	4	SCT22R/009	King Abdulaziz Medical City NG (Riyadh)
iOUTRUN: Patient-Reported OUTcomes of Benralizumab in Real-World Use in Severe EosiNophilic Asthma Patients	AstraZeneca	Ongoing	Benralizumab	4	D3250R0011	King Fahad Medical City (Riyadh) , King Faisal Specialist Hospital and Research Center (Jeddah),International Medical Center (Jeddah)
"Nintedanib in patients with bronchiolitis obliterans syndrome following hematopoietic stem cell transplantation – a multicentre phase II trial"	King Faisal Specialist Hospital & Research Centre Riyadh, Saudi Arabia	Ongoing	NINTEDANIB	2	Amendment 3 F02	King Faisal Specialist Hospital and Research Center (Riyadh)
An open-label, controlled, multi-site, Phase 2 clinical trial to assess the ureagenesis capacity in newborns and infants up to the age of 12 months with neonatal and infantile onset of urea cycle disorders (UCD) using a 15N ammonium chloride tracer compared to newborns and infants without UCD	Unicyte AG,Aawasserstrasse 2, 6370 Oberdorf NW, Switzerland	Rejected	15NH4Cl tracer assay	2	HLSC-UCD-01	King Abdulaziz Medical City NG (Riyadh)
A Phase 2 Open-label, Dose Escalation Study of HST5040 in Subjects with Propionic or Methylmalonic Acidemia Followed by a 6-Month, Randomized, Double-blind, Placebo-controlled, 2-period Crossover Study and an Open-label, Long-term Extension Study	HemoShear Therapeutics,	Terminated	ST5040 (2,2-dimethylbutanoic acid)	4	HST20-CL01	King Faisal Specialist Hospital and Research Center (Riyadh)
An observational disease and clinical outcomes registry of patients with acid lipase (LAL) deficiency	Alexion Pharma	Ongoing	Kanuma	4	ALX-LALD-5	King Faisal Specialist Hospital and Research Center (Riyadh) , King Abdulaziz Medical City NG (Riyadh)
A study comparing the effect and safety of once weekly dosing of somapacitan with daily Norditropin® as well as evaluating long-term safety of somapacitan in a basket study design in children with short stature either born small for gestational age or with Turner syndrome, Noonan syndrome, or idiopathic short stature	Novo Nordisk	Ongoing	Sogroya , Norditropin	3	NN8640-4467	King Faisal Specialist Hospital and Research Center (Riyadh) , King Abdulaziz Medical City NG (Riyadh)
Early Sedation with Dexmedetomidine vs. Placebo in Older Ventilated Critically Ill Patients A Prospective, Multi-Centre, Double-Blind, Randomized, Controlled Trial. SPICE IV	King Abdullah International Medical Research Center (KAIMRC)	Ongoing	DEXMEDETOMIDINE	4	SCT21R/006/04	King Abdulaziz Medical City NG (Riyadh), King Faisal Specialist Hospital and Research Center (Riyadh)
VICTORION REAL: An international prospective Real-world study to evaluate the Effectiveness and Adherence of incLisiran plus standard of care lipid-lowering therapy compared to standard of care therapy alone in patients with primary hypercholesterolemia or mixed dyslipidemia	Novartis	Ongoing	Inclisiran	4	CKJX839A12	Saud Al-Babtain Cardiac Center (Dammam) , King Salman Armed Forces Hospital(Tabuk) , King Fahd Armed Forces Hospital (Jeddah) , Dr. Sulaiman Al-Habib Medical Group Rayan (Riyadh),King Faisal Specialist Hospital and Research Center (Jeddah), Dr. Sulaiman Al-Habib Medical Group Olaya (Riyadh), International Medical Center (Jeddah)